Thymopoietin Antibody

Catalog Number:

25390

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P42166
Gene ID:7112

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 19 amino acid peptide near the amino terminus of human Thymopoietin.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least three isoforms of Thymopoietin are known to exist; this antibody will detect all isoforms. Thymopoietin antibody is predicted to not cross-react with other LEM domain-containing proteins.

Applications:

ELISA WB

Background:

Thymopoietin (TMPO), also known as LAP2, is a widely expressed lem-domain-containing nuclear protein that is thought to play an important role in the regulation of nuclear architecture by binding lamin B1 and chromosomes in a manner regulated by phosphorylation during mitosis. Thymopoietin associates with nucleoplasmic lamins A/C, which are encoded by the dilated cardiomyopathy (DCM) gene LMNA; mutations in Thymopoietin disrupt this binding, suggesting that Thymopoietin may be a candidate disease gene for DCM.

References:

appl_detail:

Datasheet PDF