Product Datasheet  
Thymopoietin Antibody  
Catalog Number: 25390  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:P42166
    Gene ID:7112
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against a 19 amino acid peptide near the amino terminus of human Thymopoietin.
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • other_names:  
  • TMPO, TP, LAP2, LEMD4, CMD1T
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • At least three isoforms of Thymopoietin are known to exist; this antibody will detect all isoforms. Thymopoietin antibody is predicted to not cross-react with other LEM domain-containing proteins.
  • Applications:  
  • ELISA WB
  • Background:  
  • Thymopoietin (TMPO), also known as LAP2, is a widely expressed lem-domain-containing nuclear protein that is thought to play an important role in the regulation of nuclear architecture by binding lamin B1 and chromosomes in a manner regulated by phosphorylation during mitosis. Thymopoietin associates with nucleoplasmic lamins A/C, which are encoded by the dilated cardiomyopathy (DCM) gene LMNA; mutations in Thymopoietin disrupt this binding, suggesting that Thymopoietin may be a candidate disease gene for DCM.



 
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