PRICKLE4 Antibody

Catalog Number:

25384

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q2TBC4
Gene ID:29964

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against an 18 amino acid peptide near the amino terminus of human PRICKLE4.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

Two isoforms of PRICKLE4 are known to exist. PRICKLE4 antibody is predicted to not cross-react with other PRICKLE protein family members.

Applications:

ELISA WB

Background:

PRICKLE4, also known as over-expressed breast tumor protein (OBTP), is a member of the LIM family of proteins. It possesses two LIM domains as well as a PET domain and is thought to localize to the nucleus. Its expression in multiple malignant tissue differentiations indicate that it may play a role in cancer differentiation. Two other members of the LIM family, PRICKLE1 and PRICKLE2, are thought to function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity, suggesting the PRICKLE4 may play a similar role.

References:

appl_detail:

Datasheet PDF