Product Datasheet  
PRICKLE4 Antibody  
Catalog Number: 25384  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q2TBC4
    Gene ID:29964
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against an 18 amino acid peptide near the amino terminus of human PRICKLE4.
  • reactivity：  
  • Hu
  • appl_detail：  
  • other_names：  
  • REST, NRSF-interacting LIM domain protein 4, OBTP, OEBT, TOMM6, C6orf49
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • Two isoforms of PRICKLE4 are known to exist. PRICKLE4 antibody is predicted to not cross-react with other PRICKLE protein family members.
  • Applications：  
  • ELISA WB
  • Background：  
  • PRICKLE4, also known as over-expressed breast tumor protein (OBTP), is a member of the LIM family of proteins. It possesses two LIM domains as well as a PET domain and is thought to localize to the nucleus. Its expression in multiple malignant tissue differentiations indicate that it may play a role in cancer differentiation. Two other members of the LIM family, PRICKLE1 and PRICKLE2, are thought to function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity, suggesting the PRICKLE4 may play a similar role.



 
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