UHRF1BP1L Antibody

Catalog Number:

25349

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:A0JNW5
Gene ID:23074

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 17 amino acid peptide near the center of human UHRF1BP1L.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least two isoforms of UHRF1BP1L are known to exist; this antibody will recognize both isoforms. UHRF1BP1L antibody is predicted to not cross-react with UHRF1BP1

Applications:

ELISA WB

Background:

The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1-like (UHRF1BP1L) is closely related to UHRF1BP1, also known as ICBP90, a transcription and cell cycle regulator that specifically binds to the histone H3 N-terminal tail. While little is known of UHRF1BP1L, UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells, suggesting that UHRF1BP1L may also be involved in chromatin regulation and cell proliferation.

References:

appl_detail:

Datasheet PDF