Product Datasheet
UHRF1BP1L Antibody
Catalog Number: 25349
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:A0JNW5
Gene ID:23074
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 17 amino acid peptide near the center of human UHRF1BP1L.
- other_names:
- Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1
- Purification:
- Affinity chromatography purified via peptide column
- Specificity:
- At least two isoforms of UHRF1BP1L are known to exist; this antibody will recognize both isoforms. UHRF1BP1L antibody is predicted to not cross-react with UHRF1BP1
- Background:
- The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1-like (UHRF1BP1L) is closely related to UHRF1BP1, also known as ICBP90, a transcription and cell cycle regulator that specifically binds to the histone H3 N-terminal tail. While little is known of UHRF1BP1L, UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells, suggesting that UHRF1BP1L may also be involved in chromatin regulation and cell proliferation.
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