UHRF1BP1 Antibody

Catalog Number:

25348

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q6BDS2
Gene ID:54887

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 17 amino acid peptide near the center of human UHRF1BP1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

UHRF1BP1 antibody is predicted to not cross-react with UHRF1BP1L

Applications:

ELISA WB

Background:

The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.

References:

appl_detail:

Datasheet PDF