Product Datasheet  
UHRF1BP1 Antibody  
Catalog Number: 25348  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q6BDS2
    Gene ID:54887
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 17 amino acid peptide near the center of human UHRF1BP1.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • other_names：  
  • Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1, ICBP90-binding protein 1, UHRF1 binding protein 1
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • UHRF1BP1 antibody is predicted to not cross-react with UHRF1BP1L
  • Applications：  
  • ELISA WB
  • Background：  
  • The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.



 
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