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L1TD1 Antibody

Catalog Number:

25339
other_names: LINE-1 type transposase domain containing 1, ES cell-associated protein 11, ECAT11

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q5T7N2
Gene ID:54596

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 17 amino acid peptide near the carboxy terminus of human L1TD1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

L1TD1 antibody is predicted to not cross-react with other ECAT protein family members

Applications:

ELISA WB

Background:

L1TD1 (ECAT11) is a member of the family of Embryonic Stem Cell Associated Transcripts (ECAT) that play an important role in stem cell biology. ECAT4 (Nanog) is a master regulator for the maintenance of mESC and hESC. ECAT5 was identified to be Embryonic stem cell expressed Ras (ERas), a Ras-like oncogene that is important in regulating mESC proliferation. ECAT9 (GDF3) is an important factor that helps maintain mESC pluripotency by inhibiting bone morphogenetic protein (BMP) signaling. L1TD1 is highly enriched in undifferentiated hESC and L1TD1 is a target gene of Nanog.

References:

appl_detail:

Datasheet PDF

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