Product Datasheet
L1TD1 Antibody
Catalog Number: 25339
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q5T7N2
Gene ID:54596
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 17 amino acid peptide near the carboxy terminus of human L1TD1.
- other_names:
- LINE-1 type transposase domain containing 1, ES cell-associated protein 11, ECAT11
- Purification:
- Affinity chromatography purified via peptide column
- Specificity:
- L1TD1 antibody is predicted to not cross-react with other ECAT protein family members
- Background:
- L1TD1 (ECAT11) is a member of the family of Embryonic Stem Cell Associated Transcripts (ECAT) that play an important role in stem cell biology. ECAT4 (Nanog) is a master regulator for the maintenance of mESC and hESC. ECAT5 was identified to be Embryonic stem cell expressed Ras (ERas), a Ras-like oncogene that is important in regulating mESC proliferation. ECAT9 (GDF3) is an important factor that helps maintain mESC pluripotency by inhibiting bone morphogenetic protein (BMP) signaling. L1TD1 is highly enriched in undifferentiated hESC and L1TD1 is a target gene of Nanog.
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