KCNK12 Antibody

Catalog Number:

25336

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9HB15
Gene ID:56660

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 14 amino acid peptide near the carboxy terminus of human KCNK12.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

KCNK12 antibody is predicted to not cross-react with other KCNK protein family members.

Applications:

ELISA WB

Background:

KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK12 is expressed mainly in the brain and lung, but also observed in the kidneys, heart and skeletal muscle. KCNK12 is closely related to KCNK13 (58% identity at the amino acid level), but could not yet been functionally expressed in vitro and may require other proteins to become active.

References:

appl_detail:

Datasheet PDF