Product Datasheet  
KCNK12 Antibody  
Catalog Number: 25336  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q9HB15
    Gene ID:56660
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 14 amino acid peptide near the carboxy terminus of human KCNK12.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • other_names：  
  • Potassium channel subfamily K member 12, Tandem pore domain halothane-inhibited potassium channel 2, THIK2
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • KCNK12 antibody is predicted to not cross-react with other KCNK protein family members.
  • Applications：  
  • ELISA WB
  • Background：  
  • KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK12 is expressed mainly in the brain and lung, but also observed in the kidneys, heart and skeletal muscle. KCNK12 is closely related to KCNK13 (58% identity at the amino acid level), but could not yet been functionally expressed in vitro and may require other proteins to become active.



 
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