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KCNK13 Antibody

Catalog Number:

25335
other_names: Potassium channel subfamily K member 13, Tandem pore domain halothane-inhibited potassium channel 1, THIK1

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9HB14
Gene ID:56659

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 15 amino acid peptide near the center of human KCNK13.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

KCNK13 antibody is predicted to not cross-react with other KCNK protein family members.

Applications:

ELISA WB

Background:

The closely related proteins KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK13 is expressed mainly in the brain, but is also observed in kidneys. KCNK13 has been suggested to be a candidate for the Cs+-permeable K+ channel activated by GABA(B) receptors.

References:

appl_detail:

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