Product Datasheet
KCNK13 Antibody
Catalog Number: 25335
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9HB14
Gene ID:56659
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 15 amino acid peptide near the center of human KCNK13.
- other_names:
- Potassium channel subfamily K member 13, Tandem pore domain halothane-inhibited potassium channel 1, THIK1
- Purification:
- Affinity chromatography purified via peptide column
- Specificity:
- KCNK13 antibody is predicted to not cross-react with other KCNK protein family members.
- Background:
- The closely related proteins KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK13 is expressed mainly in the brain, but is also observed in kidneys. KCNK13 has been suggested to be a candidate for the Cs+-permeable K+ channel activated by GABA(B) receptors.
© Signalway Biotechnology All Rights Reserved.