RASSF10 Antibody

Catalog Number:

25313

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:A6NK89
Gene ID:644943

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 17 amino acid peptide near the amino terminus of human RASSF10.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

RASSF10 antibody will not cross-react with other RAS association domain-containing family members.

Applications:

ELISA WB

Background:

RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.

References:

appl_detail:

Datasheet PDF