Product Datasheet  
RASSF10 Antibody  
Catalog Number: 25313  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:A6NK89
    Gene ID:644943
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at 4 ˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 17 amino acid peptide near the amino terminus of human RASSF10.
  • reactivity：  
  • Hu
  • appl_detail：  
  • other_names：  
  • RASSF10, Ras association domain-containing protein 10
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • RASSF10 antibody will not cross-react with other RAS association domain-containing family members.
  • Applications：  
  • ELISA WB
  • Background：  
  • RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.



 
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