EZH1 Antibody

Catalog Number:

25290

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q92800
Gene ID:2145

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against an 18 amino acid peptide near the amino terminus of human EZH1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

Multiple isoforms of EZH1 are known to exist. EZH1 antibody is predicted to not cross-react with EZH2

Applications:

ELISA WB

Background:

EZH1 was initially identified as a homolog of the drosophila Enhancer of Zeste through transcription mapping of chromosome 17q21. Both EZH1 and the related protein EZH2 can form complexes with the noncanonical Polycomb repressive complex-2 (PRC2) and maintain repressive chromatin, but the PRC2-EZH1 complex mediates methylation of histone H3. Both EZH1 and EZH2 are thought to function in the maintenance of embryonic stem cell pluripotency and plasticity and recently have been shown to be essential for hair follicle homeostasis and wound repair.

References:

appl_detail:

Datasheet PDF