Product Datasheet  
EZH1 Antibody  
Catalog Number: 25290  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q92800
    Gene ID:2145
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against an 18 amino acid peptide near the amino terminus of human EZH1.
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • other_names:  
  • Enhancer of zeste homolog 1, histone-lysine-N-methylase EZH1, KMT6B
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • Multiple isoforms of EZH1 are known to exist. EZH1 antibody is predicted to not cross-react with EZH2
  • Applications:  
  • ELISA WB
  • Background:  
  • EZH1 was initially identified as a homolog of the drosophila Enhancer of Zeste through transcription mapping of chromosome 17q21. Both EZH1 and the related protein EZH2 can form complexes with the noncanonical Polycomb repressive complex-2 (PRC2) and maintain repressive chromatin, but the PRC2-EZH1 complex mediates methylation of histone H3. Both EZH1 and EZH2 are thought to function in the maintenance of embryonic stem cell pluripotency and plasticity and recently have been shown to be essential for hair follicle homeostasis and wound repair.



 
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