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BAPX1 Antibody

Catalog Number:

25269
other_names: Homeobox protein Nkx-3.2, NKH3-2, NKX3B, SMMD

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:P78367
Gene ID:579

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 19 amino acid peptide near the center of human BAPX1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

BAPX1 antibody is predicted not to cross-react with other NKX homeobox proteins.

Applications:

ELISA WB

Background:

BAPX1 is the mammalian homolog of the Drosophila bagpipe homeobox gene and is expressed in the splanchnic mesoderm and embryonic skeleton. It is one of the earliest developmental markers for the sclerotome portion of the somite and the gut mesentery. BAPX1 is required for normal skeletal development; homozygous inactivating mutations in the BAPX1 gene result in spodylo-megaepiphyseal-metaphyseal dysplasia (SMMD). It has also been suggested to play a role in the proper development of the mammalian gut and is required for distal stomach development as part of a BARX1-dependent pathway.

References:

appl_detail:

Datasheet PDF

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