Product Datasheet
BAPX1 Antibody
Catalog Number: 25269
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P78367
Gene ID:579
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 19 amino acid peptide near the center of human BAPX1.
- other_names:
- Homeobox protein Nkx-3.2, NKH3-2, NKX3B, SMMD
- Purification:
- Affinity chromatography purified via peptide column
- Specificity:
- BAPX1 antibody is predicted not to cross-react with other NKX homeobox proteins.
- Background:
- BAPX1 is the mammalian homolog of the Drosophila bagpipe homeobox gene and is expressed in the splanchnic mesoderm and embryonic skeleton. It is one of the earliest developmental markers for the sclerotome portion of the somite and the gut mesentery. BAPX1 is required for normal skeletal development; homozygous inactivating mutations in the BAPX1 gene result in spodylo-megaepiphyseal-metaphyseal dysplasia (SMMD). It has also been suggested to play a role in the proper development of the mammalian gut and is required for distal stomach development as part of a BARX1-dependent pathway.
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