REQUIEM Antibody

Catalog Number:

25238

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q92785
Gene ID:5977

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against an 18 amino acid peptide near the carboxy terminus of human Requiem.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

Requiem antibody is predicted to not cross-react with other DPF protein family members.

Applications:

ELISA WB

Background:

Requiem is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It is expressed in numerous tissues in both cytosolic and nuclear regions and likely serves a regulatory role in rapid hematopoietic cell growth and turnover. Requiem has been found to act as an adaptor protein that links the NF-κB and SWI/SNF chromatin remodeling factor and is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.

References:

appl_detail:

Datasheet PDF