Product Datasheet  
REQUIEM Antibody  
Catalog Number: 25238  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q92785
    Gene ID:5977
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against an 18 amino acid peptide near the carboxy terminus of human Requiem.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • other_names：  
  • REQ, UBID4, ubi-d4, DPF2, double PHD fingers family 2
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • Requiem antibody is predicted to not cross-react with other DPF protein family members.
  • Applications：  
  • ELISA WB
  • Background：  
  • Requiem is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It is expressed in numerous tissues in both cytosolic and nuclear regions and likely serves a regulatory role in rapid hematopoietic cell growth and turnover. Requiem has been found to act as an adaptor protein that links the NF-κB and SWI/SNF chromatin remodeling factor and is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.



 
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