1-832-868-1888
order@swbio.com

Catalog Number: |
25172 |
| other_names: | SH3 domain containing ring finger 2, heart protein phosphatase 1-binding protein, Hepp1, FLJ23654 |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot:Q8TEC5 |
Form of Antibody: |
Supplied in PBS containing 0.02% sodium azide. |
Storage/Stability: |
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Immunogen: |
Raised against a 17 amino acid peptide near the carboxy terminus of human SH3RF2. |
Purification: |
Affinity chromatography purified via peptide column |
Specificity/Sensitivity: |
|
Applications: |
ELISA WB IHC |
Background: |
Although the SH3 domain containing ring finger 2 protein (SH3RF2) has been identified as a marker of the nucleus accumbens in the human brain, little is known about this protein. Recent yeast two-hybrid experiments have shown that SH3RF2 associates with protein phosphatase 1 (PP1) and is expressed primarily in heart and testis tissue. Recombinant SH3RF2 enhanced PP1 enzymatic activity and antagonized the ability of phopho-inhibitor-1 or -2 to inhibit PP1, suggesting that SH3RF2 may play a role working with PP1 in cardiac functions. |
References: |
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appl_detail: |
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