Product Datasheet  
SH3RF2 Antibody  
Catalog Number: 25172  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q8TEC5
    Gene ID:153769
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against a 17 amino acid peptide near the carboxy terminus of human SH3RF2.
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • other_names:  
  • SH3 domain containing ring finger 2, heart protein phosphatase 1-binding protein, Hepp1, FLJ23654
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • Applications:  
  • ELISA WB IHC
  • Background:  
  • Although the SH3 domain containing ring finger 2 protein (SH3RF2) has been identified as a marker of the nucleus accumbens in the human brain, little is known about this protein. Recent yeast two-hybrid experiments have shown that SH3RF2 associates with protein phosphatase 1 (PP1) and is expressed primarily in heart and testis tissue. Recombinant SH3RF2 enhanced PP1 enzymatic activity and antagonized the ability of phopho-inhibitor-1 or -2 to inhibit PP1, suggesting that SH3RF2 may play a role working with PP1 in cardiac functions.



 
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