ORMDL1 Antibody

Catalog Number:

25308

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9P0S3
Gene ID:94101

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 16 amino acid peptide of human ORMDL1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

ORMDL1 antibody is predicted to not cross-react with other ORMDL protein family members.

Applications:

ELISA WB

Background:

The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer’s disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.

References:

appl_detail:

Datasheet PDF