Product Datasheet  
ORMDL1 Antibody  
Catalog Number: 25308  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q9P0S3
    Gene ID:94101
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at 4 ˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against a 16 amino acid peptide of human ORMDL1.
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • other_names:  
  • Adoplin-1, FLJ44364, HSPC202, ORM1-like protein 1
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • ORMDL1 antibody is predicted to not cross-react with other ORMDL protein family members.
  • Applications:  
  • ELISA WB
  • Background:  
  • The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer’s disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.



 
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