SARS-CoV-2 N Protein Mouse mAb

Catalog Number:

77124

Amount:

100μg

Price:

$318

Swiss-Prot No:

P59595

Form of Antibody:

Storage/Stability:

Immunogen:

Recombinant fusion protein of SARS-CoV-2 Nucleoprotein.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

ELISA,WB

Background:

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

References:

appl_detail:

WB 1:1000 - 1:5000
ELISA 1:30000 - 1:120000

Datasheet PDF