Product Datasheet  
SARS-CoV-2 N Protein Mouse mAb  
Catalog Number: 77124  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • P59595
  • Form of Antibody：  
  • Storage：  
  • Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
  • Immunogen：  
  • Recombinant fusion protein of SARS-CoV-2 Nucleoprotein.
  • reactivity：  
  • SARS-CoV-2
  • appl_detail：  
  • WB 1:1000 - 1:5000
    ELISA 1:30000 - 1:120000
  • other_names：  
  • Nucleoprotein, NP
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • ELISA,WB
  • Background：  
  • Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.



 
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