PHB Antibody

Catalog Number:

21693

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P35232
NCBI Protein: NP_001268425.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.256~260 (N-I-T-Y-L) derived from Human PHB.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total PHB protein.

Applications:

WB

Background:

Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging. 

 

Day ME  et al. Isoform-specific targeting of PKA to multivesicular bodies. J Cell Biol 193:347-63 (2011)

Xiang F  et al. Proteomic analysis of myocardial tissue from the border zone during early stage post-infarct remodelling in rats. Eur J Heart Fail 13:254-63 (2011)

References:

appl_detail:

Western blotting: 1:500�?:1000

Datasheet PDF