Product Datasheet  
PHB Antibody  
Catalog Number: 21693  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P35232
    NCBI Protein: NP_001268425.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C
  • Immunogen：  
  • Peptide sequence around aa.256~260 (N-I-T-Y-L) derived from Human PHB.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Western blotting: 1:500�?:1000

  • other_names：  
  • Prohibitin; PHB1
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total PHB protein.
  • Applications：  
  • WB
  • Background：  

  • Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging. 

     
    Day ME  et al. Isoform-specific targeting of PKA to multivesicular bodies. J Cell Biol 193:347-63 (2011)
    Xiang F  et al. Proteomic analysis of myocardial tissue from the border zone during early stage post-infarct remodelling in rats. Eur J Heart Fail 13:254-63 (2011)



 
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