PARP2 Antibody

Catalog Number:

49880

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9UGN5

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein within the C-terminus of human PARP2.

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB,FC

Background:

Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates serine ADP-ribosylation of target proteins following interaction with HPF1; HPF1 conferring serine specificity.

References:

appl_detail:

WB: 1:500-1:1,000



FC: 1:50-1:100

Datasheet PDF