Product Datasheet
PARP2 Antibody
Catalog Number: 49880
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9UGN5
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein within the C-terminus of human PARP2.
- appl_detail:
- WB: 1:500-1:1,000
FC: 1:50-1:100
- other_names:
- ADP ribosyltransferase like 2 antibody
ADP-ribosyltransferase diphtheria toxin-like 2 antibody
ADPRT 2 antibody
ADPRT-2 antibody
ADPRT2 antibody
ADPRTL 2 antibody
ADPRTL 3 antibody
ADPRTL2 antibody
- Purification:
- ProA affinity purified
- Background:
- Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates serine ADP-ribosylation of target proteins following interaction with HPF1; HPF1 conferring serine specificity.
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