Bcl-6 Antibody

Catalog Number:	49860
other_names:	B Cell Lymphoma 6 Protein antibody B-cell CLL/lymphoma 6 antibody B-cell lymphoma 5 protein antibody B-cell lymphoma 6 protein transcript antibody BCL5 antibody BCL6A antibody cys-his2 zinc finger transcription
Amount:	100μg
calculated_mw:	79 kDa
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#:P41182
Form of Antibody:	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	Recombinant protein
Purification:	ProA affinity purified
Specificity/Sensitivity:
Applications:	WB
Background:	Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and Th1/Th2 differentiation. Bcl-6 negatively regulates NFkB expression, thereby inhibiting NFkB-mediated cellular functions. HDAC- and silent information regulator (SIR)-2-dependent acet-ylation of Bcl-6 causes downregulation of activity by inhibiting the ability of Bcl-6 to recruit complexes containing histone deacetylases (HDACs). Bcl-6 is frequently deregulated in non-Hodgkin's B cell lymphomas. The human BCL6 gene has been shown to encode a protein of 706 amino acids.
References:
appl_detail:	WB: 1:1,000-5,000
	Datasheet PDF

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