Product Datasheet  
Bcl-6 Antibody  
Catalog Number: 49860  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P41182
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu, Ms
  • appl_detail：  
  • WB: 1:1,000-5,000



  • other_names：  
  • B Cell Lymphoma 6 Protein antibody
    B-cell CLL/lymphoma 6 antibody
    B-cell lymphoma 5 protein antibody
    B-cell lymphoma 6 protein transcript antibody
    BCL5 antibody
    BCL6A antibody
    cys-his2 zinc finger transcription
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and Th1/Th2 differentiation. Bcl-6 negatively regulates NFkB expression, thereby inhibiting NFkB-mediated cellular functions. HDAC- and silent information regulator (SIR)-2-dependent acet-ylation of Bcl-6 causes downregulation of activity by inhibiting the ability of Bcl-6 to recruit complexes containing histone deacetylases (HDACs). Bcl-6 is frequently deregulated in non-Hodgkin's B cell lymphomas. The human BCL6 gene has been shown to encode a protein of 706 amino acids.



 
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