DDAH2 Antibody

Catalog Number:

49823

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O95865

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Synthetic peptide within Human DDAH2 aa 1-100

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB,IP

Background:

DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.

References:

appl_detail:

WB: 1:2,000-1:5,000


IP: 1:10-:50

Datasheet PDF