Product Datasheet
DDAH2 Antibody
Catalog Number: 49823
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O95865
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Synthetic peptide within Human DDAH2 aa 1-100
- appl_detail:
- WB: 1:2,000-1:5,000
IP: 1:10-:50
- other_names:
- DDAH antibody
DDAH II antibody
DDAH-2 antibody
DDAH2 antibody
DDAH2_HUMAN antibody
DDAHII antibody
Dimethylargininase 2 antibody
Dimethylargininase-2 antibody
Dimethylarginine dimethylaminohydrol
- Purification:
- ProA affinity purified
- Background:
- DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
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