TXNIP Antibody

Catalog Number:

49663

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9H3M7

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB, ICC/IF, IHC, FC

Background:

May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.

References:

appl_detail:

WB: 1:1,000-5,000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200

FC: 1:50-1:100

Datasheet PDF