Product Datasheet
TXNIP Antibody
Catalog Number: 49663
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9H3M7
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:1,000-5,000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
FC: 1:50-1:100
- other_names:
- EST01027 antibody
HHCPA78 antibody
THIF antibody
Thioredoxin binding protein 2 antibody
Thioredoxin interacting protein antibody
Thioredoxin-binding protein 2 antibody
Thioredoxin-interacting protein antibody
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC/IF, IHC, FC
- Background:
- May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
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