Product Datasheet  
TXNIP Antibody  
Catalog Number: 49663  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q9H3M7
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:1,000-5,000
    IHC: 1:50-1:200
    ICC/IF: 1:50-1:200

    FC: 1:50-1:100
  • other_names:  
  • EST01027 antibody
    HHCPA78 antibody
    THIF antibody
    Thioredoxin binding protein 2 antibody
    Thioredoxin interacting protein antibody
    Thioredoxin-binding protein 2 antibody
    Thioredoxin-interacting protein antibody
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC/IF, IHC, FC
  • Background:  
  • May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.



 
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