Aurora A Antibody

Catalog Number:

48861

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O14965

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

recombinant protein

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB, ICC/IF, FC

Background:

Activation of the oncogenic protein kinase Aurora A regulates meiotic and mitotic cell cycles in eukaryotic cells. Specifically, Aurora A plays a key role in G2/M progression. Activation occurs via autophosphorylation, and while 14 sites are subject to this, only the threonine residue at position 295 is required for activity. Though autophosphorylation mediates activation, a number of other proteins influence activation, including the spindle assembly factor TPX2 and p53

References:

appl_detail:

WB: 1:1,000-1:2,000

ICC: 1:100-1:500

FC: 1:50-1:100

Datasheet PDF