Product Datasheet  
Aurora A Antibody  
Catalog Number: 48861  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:O14965
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu, Ms
  • appl_detail:  
  • WB: 1:1,000-1:2,000

    ICC: 1:100-1:500

    FC: 1:50-1:100
  • other_names:  
  • AIK antibody
    ARK-1 antibody
    ARK1 antibody
    AURA antibody
    Aurka antibody
    Aurora 2 antibody
    Aurora A antibody
    Aurora kinase A antibody
    Aurora-related kinase 1 antibody
    Aurora/IPL1 like kinase antibody
    Aurora/
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC/IF, FC
  • Background:  
  • Activation of the oncogenic protein kinase Aurora A regulates meiotic and mitotic cell cycles in eukaryotic cells. Specifically, Aurora A plays a key role in G2/M progression. Activation occurs via autophosphorylation, and while 14 sites are subject to this, only the threonine residue at position 295 is required for activity. Though autophosphorylation mediates activation, a number of other proteins influence activation, including the spindle assembly factor TPX2 and p53



 
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