Product Datasheet
Aurora A Antibody
Catalog Number: 48861
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O14965
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000-1:2,000
ICC: 1:100-1:500
FC: 1:50-1:100
- other_names:
- AIK antibody ARK-1 antibody ARK1 antibody AURA antibody Aurka antibody Aurora 2 antibody Aurora A antibody Aurora kinase A antibody Aurora-related kinase 1 antibody Aurora/IPL1 like kinase antibody Aurora/
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC/IF, FC
- Background:
- Activation of the oncogenic protein kinase Aurora A regulates meiotic and mitotic cell cycles in eukaryotic cells. Specifically, Aurora A plays a key role in G2/M progression. Activation occurs via autophosphorylation, and while 14 sites are subject to this, only the threonine residue at position 295 is required for activity. Though autophosphorylation mediates activation, a number of other proteins influence activation, including the spindle assembly factor TPX2 and p53
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