CD31 Antibody

Catalog Number:

48573

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P16284

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to C-terminal residues of human CD31.

Purification:

Peptide affinity purified

Specificity/Sensitivity:

Applications:

WB, ICC, IHC, FC

Background:

PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte transmigration, angiogenesis, and integrin activation. CD31 is also expressed in certain tumors, including epithelioid hemangioendothelioma, epithelioid sarcoma-like hemangioendothelioma, other vascular tumors, histiocytic malignancies, and plasmacytomas. It is rarely found in some sarcomas, such as Kaposi's sarcoma and carcinomas. In immunohistochemistry, CD31 is used primarily to demonstrate the presence of endothelial cells in histological tissue sections. This can help to evaluate the degree of tumour angiogenesis, which can imply a rapidly growing tumor

References:

appl_detail:

WB: 1:1,000
IHC: 1:200
ICC: 1:200

FC: 1:100-1:200

Datasheet PDF