Product Datasheet  
CD31 Antibody  
Catalog Number: 48573  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P16284
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to C-terminal residues of human CD31.
  • reactivity:  
  • Hu, Ms
  • appl_detail:  
  • WB: 1:1,000
    IHC: 1:200
    ICC: 1:200

    FC: 1:100-1:200
  • other_names:  
  • Adhesion molecule antibody
    CD31 antibody
    CD31 antigen antibody
    CD31 EndoCAM antibody
    EndoCAM antibody
    FLJ34100 antibody
    FLJ58394 antibody
    GPIIA antibody
    GPIIA' antibody
    PECA1 antibody
    P
  • Purification:  
  • Peptide affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC, IHC, FC
  • Background:  
  • PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte transmigration, angiogenesis, and integrin activation. CD31 is also expressed in certain tumors, including epithelioid hemangioendothelioma, epithelioid sarcoma-like hemangioendothelioma, other vascular tumors, histiocytic malignancies, and plasmacytomas. It is rarely found in some sarcomas, such as Kaposi's sarcoma and carcinomas. In immunohistochemistry, CD31 is used primarily to demonstrate the presence of endothelial cells in histological tissue sections. This can help to evaluate the degree of tumour angiogenesis, which can imply a rapidly growing tumor



 
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