Product Datasheet
CD31 Antibody
Catalog Number: 48573
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P16284
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to C-terminal residues of human CD31.
- appl_detail:
- WB: 1:1,000
IHC: 1:200
ICC: 1:200
FC: 1:100-1:200
- other_names:
- Adhesion molecule antibody
CD31 antibody
CD31 antigen antibody
CD31 EndoCAM antibody
EndoCAM antibody
FLJ34100 antibody
FLJ58394 antibody
GPIIA antibody
GPIIA' antibody
PECA1 antibody
P
- Purification:
- Peptide affinity purified
- Applications:
- WB, ICC, IHC, FC
- Background:
- PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte transmigration, angiogenesis, and integrin activation. CD31 is also expressed in certain tumors, including epithelioid hemangioendothelioma, epithelioid sarcoma-like hemangioendothelioma, other vascular tumors, histiocytic malignancies, and plasmacytomas. It is rarely found in some sarcomas, such as Kaposi's sarcoma and carcinomas. In immunohistochemistry, CD31 is used primarily to demonstrate the presence of endothelial cells in histological tissue sections. This can help to evaluate the degree of tumour angiogenesis, which can imply a rapidly growing tumor
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