RYR2 Antibody

Catalog Number:	48554
other_names:	Arrhythmogenic right ventricular dysplasia 2 antibody ARVC2 antibody ARVD2 antibody Brain ryanodine receptor calcium release channel antibody Brain type ryanodine receptor antibody Cardiac muscle ryanodine receptor calci
Amount:	100μg
calculated_mw:	565 kDa
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#:Q92736
Form of Antibody:	1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	Synthetic peptide within human RYR2 aa 1450-1550.
Purification:	Peptide affinity purified.
Specificity/Sensitivity:
Applications:	WB,ICC,IHC,FC
Background:	Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.
References:
appl_detail:	WB: 1:500 IHC: 1:50-1:200 ICC: 1:50-1:100 FC: 1:50-1:100
	Datasheet PDF

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