Product Datasheet  
RYR2 Antibody  
Catalog Number: 48554  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q92736
  • Form of Antibody:  
  • 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide within human RYR2 aa 1450-1550.
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:500
    IHC: 1:50-1:200
    ICC: 1:50-1:100

    FC: 1:50-1:100
  • other_names:  
  • Arrhythmogenic right ventricular dysplasia 2 antibody
    ARVC2 antibody
    ARVD2 antibody
    Brain ryanodine receptor calcium release channel antibody
    Brain type ryanodine receptor antibody
    Cardiac muscle ryanodine receptor calci
  • Purification:  
  • Peptide affinity purified.
  • Specificity:  
  • Applications:  
  • WB,ICC,IHC,FC
  • Background:  
  • Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.



 
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