Product Datasheet
RYR2 Antibody
Catalog Number: 48554
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q92736
- Form of Antibody:
- 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Synthetic peptide within human RYR2 aa 1450-1550.
- appl_detail:
- WB: 1:500
IHC: 1:50-1:200
ICC: 1:50-1:100
FC: 1:50-1:100
- other_names:
- Arrhythmogenic right ventricular dysplasia 2 antibody
ARVC2 antibody
ARVD2 antibody
Brain ryanodine receptor calcium release channel antibody
Brain type ryanodine receptor antibody
Cardiac muscle ryanodine receptor calci
- Purification:
- Peptide affinity purified.
- Applications:
- WB,ICC,IHC,FC
- Background:
- Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.
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