ApoER2 Antibody

Catalog Number:

48551

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q14114

Form of Antibody:

1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein within human ApoER2 500-750 aa.

Purification:

Protein affinity purified

Specificity/Sensitivity:

Applications:

WB,ICC,IHC,FC

Background:

ApoER2 (apolipoprotein E receptor 2), also designated LRP8, is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. ApoER2 is expressed in brain and placenta and has several splice variants. ApoER2 is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

References:

appl_detail:

WB: 1:500-1:1,000
IHC: 1:50
ICC: 1:50-1:200

FC: 1:50-1:100

Datasheet PDF