Product Datasheet  
ApoER2 Antibody  
Catalog Number: 48551  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q14114
  • Form of Antibody：  
  • 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein within human ApoER2 500-750 aa.
  • reactivity：  
  • Hu, Ms
  • appl_detail：  
  • WB: 1:500-1:1,000
    IHC: 1:50
    ICC: 1:50-1:200

    FC: 1:50-1:100
  • other_names：  
  • APOER2 antibody
    Apolipoprotein E receptor 2 antibody
    low density lipoprotein receptor-related protein 8 antibody
    Low-density lipoprotein receptor-related protein 8 antibody
    LRP-8 antibody
    LRP8 antibody
    LRP8_HU
  • Purification：  
  • Protein affinity purified
  • Specificity：  
  • Applications：  
  • WB,ICC,IHC,FC
  • Background：  
  • ApoER2 (apolipoprotein E receptor 2), also designated LRP8, is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. ApoER2 is expressed in brain and placenta and has several splice variants. ApoER2 is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.



 
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