Dynamin 1 Antibody

Catalog Number:

48539

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q05193

Form of Antibody:

1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein within human Dynamin 1 aa 575-750.

Purification:

Protein affinity purified

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

Members of the Dynamin family, including Dynamin I and Dynamin II, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression found in testis. Both dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the dynamins and effectors of their GTPase activity). The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to clathrin coated pits by SH3 domain interaction with amphiphysin, a protein highly expressed in brain.

References:

appl_detail:

WB: 1:500-1:1,000
IHC: 1:50-1:200

Datasheet PDF