Product Datasheet  
Dynamin 1 Antibody  
Catalog Number: 48539  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q05193
  • Form of Antibody:  
  • 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein within human Dynamin 1 aa 575-750.
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:500-1:1,000
    IHC: 1:50-1:200


  • other_names:  
  • B dynamin antibody
    D100 antibody
    DNM 1 antibody
    DNM antibody
    DNM1 antibody
    DYN1_HUMAN antibody
    Dynamin antibody
    Dynamin-1 antibody
    Dynamin1 antibody
  • Purification:  
  • Protein affinity purified
  • Specificity:  
  • Applications:  
  • WB,IHC
  • Background:  
  • Members of the Dynamin family, including Dynamin I and Dynamin II, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression found in testis. Both dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the dynamins and effectors of their GTPase activity). The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to clathrin coated pits by SH3 domain interaction with amphiphysin, a protein highly expressed in brain.



 
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