Alpha-1 acid glycoprotein Antibody

Catalog Number:

48525

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P02763

Form of Antibody:

1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein

Purification:

Protein affinity purified

Specificity/Sensitivity:

Applications:

WB,IHC,FC

Background:

AGP (α1-acid glycoprotein) is an acute phase plasma protein synthesized by the liver. It functions to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, it also mediates the extravasation of cells during infection and inflammation. Expression of AGP is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides. AGP has a high affinity, low capacity binding for basic drugs at physiological pH. In human plasma, AGP is found at levels of 0.5-1.4 mg/ml, though this is elevated during acute inflammation, and, as a result, levels of this protein can be used to diagnose inflammatory conditions. AGP-1 and AGP-2 contain five and six potential N-glycosylation sites, respectively. Abnormal expression of the APG-1 gene is linked to sarcoidosis and other immunogenetic diseases, while mutations in the APG-2 gene are associated with different types of carcinomas.

References:

appl_detail:

WB: 1:500-1:2000
IHC: 1:50-1:200


FC: 1:50-1:100

Datasheet PDF