Product Datasheet  
Alpha-1 acid glycoprotein Antibody  
Catalog Number: 48525  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P02763
  • Form of Antibody：  
  • 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:500-1:2000
    IHC: 1:50-1:200


    FC: 1:50-1:100
  • other_names：  
  • A1AG1_HUMAN antibody
    AGP 1 antibody
    AGP A antibody
    AGP antibody
    AGP1 antibody
    Alpha 1 acid glycoprotein antibody
    Alpha-1-acid glycoprotein 1 antibody
    alpha-1-AGP antibody
    Epididymis secretory sp
  • Purification：  
  • Protein affinity purified
  • Specificity：  
  • Applications：  
  • WB,IHC,FC
  • Background：  
  • AGP (α1-acid glycoprotein) is an acute phase plasma protein synthesized by the liver. It functions to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, it also mediates the extravasation of cells during infection and inflammation. Expression of AGP is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides. AGP has a high affinity, low capacity binding for basic drugs at physiological pH. In human plasma, AGP is found at levels of 0.5-1.4 mg/ml, though this is elevated during acute inflammation, and, as a result, levels of this protein can be used to diagnose inflammatory conditions. AGP-1 and AGP-2 contain five and six potential N-glycosylation sites, respectively. Abnormal expression of the APG-1 gene is linked to sarcoidosis and other immunogenetic diseases, while mutations in the APG-2 gene are associated with different types of carcinomas.



 
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